Μυελοειδές καρκίνωμα θυρεοειδούς σαν τυχαίο εύρημα μετά από λοβεκτομή

GRAVES’ DISEASE –IS PREOPERATIVE ADMINISTRATION OF IODINE INDICATED?

In Graves’ disease (GD), short-term administration of iodine is recommended for the preoperative preparation of the patient for thyroidectomy. This strategy decreases thyroid vascularity and diminishes blood loss during surgery. Moreover, in not-euthyroid patients, lowers serum thyroid hormone concentrations. Some authors found that preoperative administration of iodine in GD is associated with a lower incidence of transient hypoparathyroidism and hoarseness, compared with those who have not received iodine preoperatively. In patients with GD from regions with iodine deficiency or with toxic adenoma or toxic nodular goiter, iodine administration may exacerbate hyperthyroidism, because the iodine provides more substrate for new hormone synthesis and in these patients, iodine should not be routinely used for the preoperative preparation of the patients. If iodine is used to help decrease thyroid hormone concentrations, is should not be administered until one hour after a thionamide has been given to block thyroid hormone synthesis.