WHAT’S THE ROLE OF EXTERNAL RADIATION THERAPY (ERT) IN THE MANAGEMENT OF PATIENTS WITH DIFFERENTIATED THYROID CANCER?
Traditionally, well-differentiated thyroid cancer has been considered radioresistant. Recent experience, however, indicates that ERT could be useful in selected cases, including:
ü  Poorly differentiated papillary, follicular, or Hürthle cell thyroid cancer
ü  Extrathyroidal extension
ü  Tumors not concentrating radioactive iodine / radioiodine non-avid tumors
ü  Gross or microscopic residual tumor (for example in patients with locally advanced thyroid cancer, especially in older patients)
ü  Inoperable thyroid cancer
ü  As adjuvant therapy following surgery for recurrent thyroid cancer
ü  For pain relief in patients with bone metastases from thyroid cancer
Based on current literature, there is evidence that ERT can significantly improve local control of the disease and reduce the incidence of tumor recurrence.


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