FINE-NEEDLE ASPIRATION BIOPSY-WHEN IS IT INDICATED IN PRACTICE?
Guidelines and clinical practice patterns regarding indications for FNA biopsy in patients with incidental thyroid nodules (ITNs) vary. Most clinicians, however, recommend FNA biopsy for any solid or hypoechoic nodule > 10 mm in diameter or when there are suspicious clinical or sonographic features (presented in the attached table), regardless of nodule’ size.
SUSPICIOUS CLINICAL FINDINGS
SUSPICIOUS ULTRASONOGRAPHIC FINDINGS
Family history of thyroid cancer
Microcalcifications
Previous neck irradiation (especially during childhood)
Irregular borders
Some genetic syndromes (rare, such as MEN II, Cowden syndrome, Carney complex etc)
Extrathyroidal extension
Fixed, very hard nodule
Pathologically enlarged lymph nodes
Coexistent neck lymphadenopathy
Increased chaotic internal vascularization

Taller-than-wide morphology


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