FNA
CYTOLOGY OF SUSPICIOUS LYMPH NODES IN THYROID CANCER
Ultrasound (US)
and US-guided Fine-Needle Aspiration (FNA) cytology are the main diagnostic
tools for detecting cervical metastases of thyroid cancer (TC) either
preoperatively or during follow-up (recurrence after surgery). Results of
US-guided FNA cytology in US suspicious lymph nodes can be categorized as:
I.Presence
of malignant cells (frequency of metastases [FM] 96 %)
II.Presence
of macrophages without malignant cells (FM 87.5 %)
III.Cell paucity
(FM 71.4 %)
IV.Negative
for malignancy (FM=35 %).
Obviously,
when metastatic lymph nodes are diagnosed on cytology, concomitant lymph node
dissection should be performed at the time of thyroidectomy (preferentially,
selective or compartment-oriented). In the case of regional recurrence, lymph
node’ size is another important factor which should be taken into consideration
to select optimal treatment strategy. However, given the high false-negative
rates, it should be emphasized that ultrasonographically suspicious lymph nodes
should not be neglected, even when FNA cytology is negative for malignancy. Thyroglobulin
(Tg) measurement in the washout may increase the diagnostic accuracy of FNA.
See more: www.gsakorafas.grFacebook page: Χειρουργική Θυρεοειδούς - παραθυρεοειδών / Γεώργιος Σακοράφας and
Fabebook page: Thyroid - Parathyroid Surgery / George Sakorafas
Σχόλια
Δημοσίευση σχολίου