METASTATIC DIFFERENTIATED THYROID CANCER – INCIDENCE
AND PROGNOSIS
Distant metastases from differentiated
follicular-derived thyroid cancer occur in 6 – 7 patients/million population.
Metastatic disease is most commonly located in lungs and bones and is the main
cause of thyroid cancer-related deaths, with mortality rates of 65 % and 75 %
at 5 and 10 years after the diagnosis of metastases. Major therapeutic advances
have been achieved for metastatic thyroid cancers during recent decades, including
better definition of the aims of levothyroxine treatment, thermal ablation,
stereotactic external beam radiation, radioactive iodine treatment and new
treatment modalities for radioiodine-refractory disease.
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