Μυελοειδές καρκίνωμα θυρεοειδούς σαν τυχαίο εύρημα μετά από λοβεκτομή

MATERNAL COMPLICATIONS OF PRIMARY HYPERPARATHYROIDISM DURING PREGNANCY

Although primary hyperparathyroidism (PHPT) affects mainly women of older age groups, about 5 - 10 % of cases are diagnosed in women of childbearing age. The true prevalence of PHPT-associated complications during pregnancy is unknown. Maternal complications of PHPT during pregnancy include:

1.Nephrolithiasis – the most common maternal complication

2.Pancreatitis- incidence of about 10 %, ominous sign of disease severity during the 2^nd or 3^rd trimester. Interestingly, its prevalence is higher than in PHPT in non-pregnant women (1 %), a finding that indicates that it is favored by pregnancy

3.Preeclampsia, especially when PHPT is associated with vitamin D deficiency prior to delivery

4.Severe hypercalcemia or parathyroid crisis – typically during the 3^rd trimester or in the post-partum period

5.Other complications ranging from non-specific clinical manifestations to end-organ calcification (e.g. cardiac arrythmias, osteopenia, peptic ulcer, renal impairment etc)